NSO 507 Neurobiology of Disease
This course integrates basic neuroscience with clinical neurology to elucidate principles of neurological diseases. Neurological impairment resulting from endogenous and exogenous nervous system damage will be elucidated through the study of animal models. The objective will be to demonstrate the underlying pathological consequences of lesions and strategies for neuroprotection and regeneration. Examples of nervous system damage to be addressed include neurodegenerative diseases, epilepsy, stroke, and traumatic brain and spinal cord injury. The pathophysiology of infectious toxins, chemical warfare agents, and radioactive insults will be used to explore the roles that altered synaptic transmission, energy metabolism, and DNA repair play neurological disease.